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FcγRIIB in autoimmunity and infection: evolutionary and therapeutic implications

FcγRIIB is the only inhibitory Fc receptor. It controls many aspects of immune and inflammatory responses, and variation in the gene encoding this protein has long been associated with susceptibility to autoimmune disease, particularly systemic lupus erythematosus (SLE). FcγRIIB is also involved in...

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Detalles Bibliográficos
Main Authors: Smith, Kenneth G. C., Clatworthy, Menna R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148599/
https://ncbi.nlm.nih.gov/pubmed/20414206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2762
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