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FcγRIIb Balances Efficient Pathogen Clearance and the Cytokine-mediated Consequences of Sepsis

The immune response to infection must be controlled to ensure it is optimal for defense while avoiding the consequences of excessive inflammation, which include fatal septic shock. Mice deficient in FcγRIIb, an inhibitory immunoglobulin G Fc receptor, have enhanced immune responses. Therefore, we ex...

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Autori principali: Clatworthy, Menna R., Smith, Kenneth G.C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213308/
https://ncbi.nlm.nih.gov/pubmed/14981111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20032197
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