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The Complex Association of FcγRIIb With Autoimmune Susceptibility
FcγRIIb is the only inhibitory Fc receptor and controls many aspects of immune and inflammatory responses. The observation 19 years ago that FcγRIIb(−/−) mice generated by gene targeting in 129 derived ES cells developed severe lupus like disease when backcrossed more than 7 generations into C57BL/6...
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| 發表在: | Front Immunol |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6803437/ https://ncbi.nlm.nih.gov/pubmed/31681256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02061 |
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