T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc N-linked glycosylation patterns. IgG Abs that are...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hess, Constanze, Winkler, André, Lorenz, Alexandra K., Holecska, Vivien, Blanchard, Véronique, Eiglmeier, Susanne, Schoen, Anna-Lena, Bitterling, Josephine, Stoehr, Alexander D., Petzold, Dominique, Schommartz, Tim, Mertes, Maria M.M., Schoen, Carolin T., Tiburzy, Ben, Herrmann, Anne, Köhl, Jörg, Manz, Rudolf A., Madaio, Michael P., Berger, Markus, Wardemann, Hedda, Ehlers, Marc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754242/
https://ncbi.nlm.nih.gov/pubmed/23979161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65938
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