Conformational stability of digestion-resistant peptides of peanut conglutins reveals the molecular basis of their allergenicity

Conglutins represent the major peanut allergens and are renowned for their resistance to gastro-intestinal digestion. Our aim was to characterize the digestion-resistant peptides (DRPs) of conglutins by biochemical and biophysical methods followed by a molecular dynamics simulation in order to bette...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Apostolovic, Danijela, Stanic-Vucinic, Dragana, de Jongh, Harmen H. J., de Jong, Govardus A. H., Mihailovic, Jelena, Radosavljevic, Jelena, Radibratovic, Milica, Nordlee, Julie A., Baumert, Joseph L., Milcic, Milos, Taylor, Steve L., Garrido Clua, Nuria, Cirkovic Velickovic, Tanja, Koppelman, Stef J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932508/
https://ncbi.nlm.nih.gov/pubmed/27377129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29249
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