Conformational stability of digestion-resistant peptides of peanut conglutins reveals the molecular basis of their allergenicity

Conglutins represent the major peanut allergens and are renowned for their resistance to gastro-intestinal digestion. Our aim was to characterize the digestion-resistant peptides (DRPs) of conglutins by biochemical and biophysical methods followed by a molecular dynamics simulation in order to bette...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Apostolovic, Danijela, Stanic-Vucinic, Dragana, de Jongh, Harmen H. J., de Jong, Govardus A. H., Mihailovic, Jelena, Radosavljevic, Jelena, Radibratovic, Milica, Nordlee, Julie A., Baumert, Joseph L., Milcic, Milos, Taylor, Steve L., Garrido Clua, Nuria, Cirkovic Velickovic, Tanja, Koppelman, Stef J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932508/
https://ncbi.nlm.nih.gov/pubmed/27377129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29249
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