Conformational stability of digestion-resistant peptides of peanut conglutins reveals the molecular basis of their allergenicity

Conglutins represent the major peanut allergens and are renowned for their resistance to gastro-intestinal digestion. Our aim was to characterize the digestion-resistant peptides (DRPs) of conglutins by biochemical and biophysical methods followed by a molecular dynamics simulation in order to bette...

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Publicado en:Sci Rep
Autores principales: Apostolovic, Danijela, Stanic-Vucinic, Dragana, de Jongh, Harmen H. J., de Jong, Govardus A. H., Mihailovic, Jelena, Radosavljevic, Jelena, Radibratovic, Milica, Nordlee, Julie A., Baumert, Joseph L., Milcic, Milos, Taylor, Steve L., Garrido Clua, Nuria, Cirkovic Velickovic, Tanja, Koppelman, Stef J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932508/
https://ncbi.nlm.nih.gov/pubmed/27377129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29249
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