Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis

Clusterin (CLU) is a stress‐activated molecular chaperone that confers treatment resistance to taxanes when highly expressed. While CLU inhibition potentiates activity of taxanes and other anti‐cancer therapies in preclinical models, progression to treatment‐resistant disease still occurs implicatin...

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Bibliografische gegevens
Gepubliceerd in:EMBO Mol Med
Hoofdauteurs: Al Nakouzi, Nader, Wang, Chris Kedong, Beraldi, Eliana, Jager, Wolfgang, Ettinger, Susan, Fazli, Ladan, Nappi, Lucia, Bishop, Jennifer, Zhang, Fan, Chauchereau, Anne, Loriot, Yohann, Gleave, Martin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931290/
https://ncbi.nlm.nih.gov/pubmed/27198502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506059
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