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Regulation of mitosis and taxane response by Daxx and Rassf1

Current theories suggest that mitotic checkpoint proteins are essential for proper cellular response to taxanes, a widely-used family of chemotherapeutic compounds. We recently demonstrated that absence or depletion of protein Daxx increases cellular taxol (paclitaxel) resistance—a common trait of p...

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Detalhes bibliográficos
Main Authors: Giovinazzi, Serena, Lindsay, Cory R., Morozov, Viacheslav M., Escobar-Cabrera, Eric, Summers, Matthew K., Han, Hyo Sook, McIntosh, Lawrence P., Ishov, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954566/
https://ncbi.nlm.nih.gov/pubmed/21643015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.211
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