Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis

Clusterin (CLU) is a stress‐activated molecular chaperone that confers treatment resistance to taxanes when highly expressed. While CLU inhibition potentiates activity of taxanes and other anti‐cancer therapies in preclinical models, progression to treatment‐resistant disease still occurs implicatin...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:EMBO Mol Med
Asıl Yazarlar: Al Nakouzi, Nader, Wang, Chris Kedong, Beraldi, Eliana, Jager, Wolfgang, Ettinger, Susan, Fazli, Ladan, Nappi, Lucia, Bishop, Jennifer, Zhang, Fan, Chauchereau, Anne, Loriot, Yohann, Gleave, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931290/
https://ncbi.nlm.nih.gov/pubmed/27198502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201506059
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