Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization

Protein phosphatase 2A (PP2A) accounts for the majority of total Ser/Thr phosphatase activities in most cell types and regulates many biological processes. PP2A holoenzymes contain a scaffold A subunit, a catalytic C subunit, and one of the regulatory/targeting B subunits. How the B subunit controls...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Wang, Jiao, Wang, Zhizhi, Yu, Tingting, Yang, Huan, Virshup, David M., Kops, Geert J. P. L., Lee, Sang Hyun, Zhou, Weihong, Li, Xin, Xu, Wenqing, Rao, Zihe
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930772/
https://ncbi.nlm.nih.gov/pubmed/27350047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-016-0283-4
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