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BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner

The spindle assembly checkpoint (SAC) is a signalling network that delays anaphase onset until all the chromosomes are attached to the mitotic spindle through their kinetochores. The downstream target of the spindle checkpoint is the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin liga...

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Bibliografiske detaljer
Main Authors: Lara-Gonzalez, Pablo, Scott, Maria I. F., Diez, Maria, Sen, Onur, Taylor, Stephen S.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258114/
https://ncbi.nlm.nih.gov/pubmed/22193957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.094763
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