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BubR1 blocks substrate recruitment to the APC/C in a KEN-box-dependent manner
The spindle assembly checkpoint (SAC) is a signalling network that delays anaphase onset until all the chromosomes are attached to the mitotic spindle through their kinetochores. The downstream target of the spindle checkpoint is the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin liga...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258114/ https://ncbi.nlm.nih.gov/pubmed/22193957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.094763 |
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