The tumor-associated glycosyltransferase ST6Gal-I regulates stem cell transcription factors and confers a cancer stem cell phenotype

The glycosyltransferase ST6Gal-I which adds α2-6-linked sialic acids to substrate glycoproteins has been implicated in carcinogenesis, however, the nature of its pathogenic role remains poorly understood. Here we show that ST6Gal-I is upregulated in ovarian and pancreatic carcinomas, enriched in met...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Schultz, Matthew J., Holdbrooks, Andrew T., Chakraborty, Asmi, Grizzle, William E., Landen, Charles N., Buchsbaum, Donald J., Conner, Michael G., Arend, Rebecca C., Yoon, Karina J, Klug, Christopher A., Bullard, Daniel C., Kesterson, Robert A., Oliver, Patsy G., O’Connor, Amber K., Yoder, Bradley K., Bellis, Susan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930726/
https://ncbi.nlm.nih.gov/pubmed/27216178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2834
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