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ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines

The ST6Gal-I sialyltransferase adds an α2–6-linked sialic acid to the N-glycans of certain receptors. ST6Gal-I mRNA has been reported to be upregulated in human cancer, but a prior lack of antibodies has limited immunochemical analysis of the ST6Gal-I protein. Here we show upregulated ST6Gal-I prote...

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Detalhes bibliográficos
Main Authors: Swindall, Amanda F., Londoño-Joshi, Angelina I., Schultz, Matthew J., Fineberg, Naomi, Buchsbaum, Donald J., Bellis, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038408/
https://ncbi.nlm.nih.gov/pubmed/23358684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3424
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