ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells

BACKGROUND: Platinum drugs, including cisplatin, are a frontline therapeutic in ovarian cancer treatment and acquired resistance to these agents is a major contributor to ovarian cancer morbidity and mortality. In this study a novel glycosylation-dependent mechanism for cisplatin resistance is descr...

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Bibliografiske detaljer
Main Authors: Schultz, Matthew J, Swindall, Amanda F, Wright, John W, Sztul, Elizabeth S, Landen, Charles N, Bellis, Susan L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637436/
https://ncbi.nlm.nih.gov/pubmed/23578204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-6-25
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