ST6Gal-I Regulates Macrophage Apoptosis via α2-6 Sialylation of the TNFR1 Death Receptor

Macrophages play a central role in innate immunity, however mechanisms regulating macrophage survival are not fully understood. Herein we describe a novel apoptotic pathway involving α2-6 sialylation of the TNFR1 death receptor by the ST6Gal-I sialyltransferase. Variant glycosylation of TNFR1 has no...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Zhongyu, Swindall, Amanda F., Kesterson, Robert A., Schoeb, Trenton R., Bullard, Daniel C., Bellis, Susan L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Glycobiology and Extracellular Matrices
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234788/
https://ncbi.nlm.nih.gov/pubmed/21930713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.276063
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak