Prostate tumor DNA methylation is associated with cigarette smoking and adverse prostate cancer outcomes

BACKGROUND: DNA methylation has been hypothesized as a mechanism to explain the association between smoking and adverse prostate cancer (PCa) outcomes. We aimed to assess whether smoking was associated with prostate tumor DNA methylation and whether these alterations may explain, in part, the associ...

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Pubblicato in:Cancer
Autori principali: Shui, Irene M, Wong, Chao-Jen, Zhao, Shanshan, Kolb, Suzanne, Ebot, Ericka M, Geybels, Milan, Rubicz, Rohina, Wright, Jonathan L., Lin, Daniel W., Klotzle, Brandy, Bibikova, Marina, Fan, Jian-Bing, Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930391/
https://ncbi.nlm.nih.gov/pubmed/27142338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30045
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