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Prostate tumor DNA methylation is associated with cigarette smoking and adverse prostate cancer outcomes

BACKGROUND: DNA methylation has been hypothesized as a mechanism to explain the association between smoking and adverse prostate cancer (PCa) outcomes. We aimed to assess whether smoking was associated with prostate tumor DNA methylation and whether these alterations may explain, in part, the associ...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Shui, Irene M, Wong, Chao-Jen, Zhao, Shanshan, Kolb, Suzanne, Ebot, Ericka M, Geybels, Milan, Rubicz, Rohina, Wright, Jonathan L., Lin, Daniel W., Klotzle, Brandy, Bibikova, Marina, Fan, Jian-Bing, Ostrander, Elaine A., Feng, Ziding, Stanford, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930391/
https://ncbi.nlm.nih.gov/pubmed/27142338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30045
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