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Validation study of genes with hypermethylated promoter regions associated with prostate cancer recurrence

BACKGROUND: One challenge in prostate cancer (PCa) is distinguishing indolent from aggressive disease at diagnosis. DNA promoter hypermethylation is a frequent epigenetic event in PCa, but few studies of DNA methylation in relation to features of more aggressive tumors or PCa recurrence have been co...

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Detalhes bibliográficos
Main Authors: Stott-Miller, Marni, Zhao, Shanshan, Wright, Jonathan L., Kolb, Suzanne, Bibikova, Marina, Klotzle, Brandy, Ostrander, Elaine A., Fan, Jian-Bing, Feng, Ziding, Stanford, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082437/
https://ncbi.nlm.nih.gov/pubmed/24718283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-13-1000
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