PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profiles

BACKGROUND: Prostate cancer (PCa) with loss of the tumor suppressor gene PTEN has an unfavorable prognosis. DNA methylation profiles associated with PTEN loss may provide further insights into the mechanisms underlying these more aggressive, clinically relevant tumors. METHODS: The cohort included p...

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Udgivet i:Oncotarget
Main Authors: Geybels, Milan S., Fang, Min, Wright, Jonathan L., Qu, Xiaoyu, Bibikova, Marina, Klotzle, Brandy, Fan, Jian-Bing, Feng, Ziding, Ostrander, Elaine A., Nelson, Peter S., Stanford, Janet L.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663600/
https://ncbi.nlm.nih.gov/pubmed/29137428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20940
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