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PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profiles

BACKGROUND: Prostate cancer (PCa) with loss of the tumor suppressor gene PTEN has an unfavorable prognosis. DNA methylation profiles associated with PTEN loss may provide further insights into the mechanisms underlying these more aggressive, clinically relevant tumors. METHODS: The cohort included p...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Geybels, Milan S., Fang, Min, Wright, Jonathan L., Qu, Xiaoyu, Bibikova, Marina, Klotzle, Brandy, Fan, Jian-Bing, Feng, Ziding, Ostrander, Elaine A., Nelson, Peter S., Stanford, Janet L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663600/
https://ncbi.nlm.nih.gov/pubmed/29137428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20940
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