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How Can Viral Dynamics Models Inform Endpoint Measures in Clinical Trials of Therapies for Acute Viral Infections?

Acute viral infections pose many practical challenges for the accurate assessment of the impact of novel therapies on viral growth and decay. Using the example of influenza A, we illustrate how the measurement of infection-related quantities that determine the dynamics of viral load within the human...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vegvari, Carolin, Hadjichrysanthou, Christoforos, Cauët, Emilie, Lawrence, Emma, Cori, Anne, de Wolf, Frank, Anderson, Roy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930163/
https://ncbi.nlm.nih.gov/pubmed/27367230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158237
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