The importance of endpoint selection: How effective does a drug need to be for success in a clinical trial of a possible Alzheimer’s disease treatment?

To date, Alzheimer’s disease (AD) clinical trials have been largely unsuccessful. Failures have been attributed to a number of factors including ineffective drugs, inadequate targets, and poor trial design, of which the choice of endpoint is crucial. Using data from the Alzheimer’s Disease Neuroimag...

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Dettagli Bibliografici
Pubblicato in:Eur J Epidemiol
Autori principali: Evans, Stephanie, McRae-McKee, Kevin, Wong, Mei Mei, Hadjichrysanthou, Christoforos, De Wolf, Frank, Anderson, Roy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2018
Soggetti:
Neuro-Epidemiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061129/
https://ncbi.nlm.nih.gov/pubmed/29572656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10654-018-0381-0
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