Cytoplasmic Cyclin E and Phospho–Cyclin-Dependent Kinase 2 Are Biomarkers of Aggressive Breast Cancer

Cyclin E and its co-activator, phospho–cyclin-dependent kinase 2 (p-CDK2), regulate G(1) to S phase transition and their deregulation induces oncogenesis. Immunohistochemical assessments of these proteins in cancer have been reported but were based only on their nuclear expression. However, the onco...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Pathol
Κύριοι συγγραφείς: Karakas, Cansu, Biernacka, Anna, Bui, Tuyen, Sahin, Aysegul A., Yi, Min, Akli, Said, Schafer, Jolie, Alexander, Angela, Adjapong, Opoku, Hunt, Kelly K., Keyomarsi, Khandan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Investigative Pathology 2016
Θέματα:
Regular Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929404/
https://ncbi.nlm.nih.gov/pubmed/27182644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.02.024
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