Cytoplasmic Cyclin E Predicts Recurrence in Patients with Breast Cancer

BACKGROUND: Low-molecular-weight-cyclin E (LMW-E) detected by Western blot, predicts for reduced breast cancer survival, however, it is impractical for clinical use. LMW-E lacks a nuclear localization signal which leads to accumulation in the cytoplasm that can be detected by immunohistochemistry. W...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Hunt, Kelly K., Karakas, Cansu, Ha, Min Jin, Biernacka, Anna, Yi, Min, Sahin, Aysegul A., Adjapong, Opoku, Hortobagyi, Gabriel N., Bondy, Melissa, Thompson, Patricia, Cheung, Kwok Leung, Ellis, Ian O., Bacus, Sarah, Symmans, W. Fraser, Do, Kim-Anh, Keyomarsi, Khandan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5441976/
https://ncbi.nlm.nih.gov/pubmed/27881578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2217
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