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Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer

PURPOSE: Preoperative aromatase inhibitor (AI) therapy has demonstrated efficacy in hormone receptor (HR)-positive postmenopausal breast cancer. However, many patients have disease that is either intrinsically resistant to AIs or that responds initially but develops resistance after prolonged exposu...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Doostan, Iman, Karakas, Cansu, Kohansal, Mehrnoosh, Low, Kwang-Hui, Ellis, Matthew J., Olson, John A., Suman, Vera J., Hunt, Kelly K., Moulder, Stacy L., Keyomarsi, Khandan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768442/
https://ncbi.nlm.nih.gov/pubmed/28947566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1544
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