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Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing

Yeast Rad52 (yRad52) has two important functions at homologous DNA recombination (HR); annealing complementary single-strand DNA (ssDNA) molecules and recruiting Rad51 recombinase onto ssDNA (recombination mediator activity). Its human homolog (hRAD52) has a lesser role in HR, and apparently lacks m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Khade, Nilesh V., Sugiyama, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928909/
https://ncbi.nlm.nih.gov/pubmed/27362509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158436
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