In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation

Homologous recombination (HR) uses a homologous template to accurately repair DNA double-strand breaks and stalled replication forks to maintain genome stability. During homology search, Rad51 nucleoprotein filaments probe and interact with dsDNA, forming the synaptic complex that is stabilized on a...

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Udgivet i:Nat Commun
Main Authors: Tavares, Eliana Moreira, Wright, William Douglass, Heyer, Wolf-Dietrich, Le Cam, Eric, Dupaigne, Pauline
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731316/
https://ncbi.nlm.nih.gov/pubmed/31492866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12082-z
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