Llwytho...

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered ssDNA

BRCA2 is an important tumor suppressor and functions in homologous recombination, a key genomic integrity pathway. BRCA2 interacts with RAD51, the central protein of recombination, which forms filaments on ssDNA to perform homology search and DNA strand invasion. We report the purification of full-l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Jie, Doty, Tammy, Gibson, Bryan, Heyer, Wolf-Dietrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952495/
https://ncbi.nlm.nih.gov/pubmed/20729859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1904
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