PCR-based analysis of mitochondrial DNA copy number, mitochondrial DNA damage, and nuclear DNA damage

Because of the role DNA damage and depletion play in human disease, it is important to develop and improve tools to assess these endpoints. This unit describes PCR-based methods to measure nuclear and mitochondrial DNA damage and copy number. Long amplicon quantitative polymerase chain reaction (LA-...

Full description

Saved in:
Bibliographic Details
Published in:Curr Protoc Toxicol
Main Authors: Gonzalez-Hunt, Claudia P., Rooney, John P., Ryde, Ian T., Anbalagan, Charumathi, Joglekar, Rashmi, Meyer, Joel N.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928199/
https://ncbi.nlm.nih.gov/pubmed/26828332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471140856.tx2011s67
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items