Increased circulating concentrations of mesencephalic astrocyte-derived neurotrophic factor in children with type 1 diabetes

Mesencephalic astrocyte-derived neurotrophic factor (MANF) was recently shown to be essential for the survival and proliferation of pancreatic β-cells in mice, where deletion of MANF resulted in diabetes. The current study aimed at determining whether the concentration of circulating MANF is associa...

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Published in:Sci Rep
Main Authors: Galli, Emilia, Härkönen, Taina, Sainio, Markus T., Ustav, Mart, Toots, Urve, Urtti, Arto, Yliperttula, Marjo, Lindahl, Maria, Knip, Mikael, Saarma, Mart, Lindholm, Päivi
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4928177/
https://ncbi.nlm.nih.gov/pubmed/27356471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29058
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