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Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy

Cerebral dopamine neurotrophic factor (CDNF) shows beneficial effects in rodent models of Parkinson’s and Alzheimer’s disease. The brain is a challenging target for protein therapy due to its exclusive blood–brain barrier. Hence, the therapeutic protein should be delivered directly to the brain pare...

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Detalhes bibliográficos
Publicado no:Cell Transplant
Main Authors: Galli, Emilia, Lindholm, Päivi, Kontturi, Leena-Stiina, Saarma, Mart, Urtti, Arto, Yliperttula, Marjo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628564/
https://ncbi.nlm.nih.gov/pubmed/30841717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689719827943
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