Characterization of the Structural and Functional Determinants of MANF/CDNF in Drosophila In Vivo Model

Mammalian MANF and CDNF proteins are evolutionarily conserved neurotrophic factors that can protect and repair mammalian dopaminergic neurons in vivo. In Drosophila, the sole MANF protein (DmManf) is needed for the maintenance of dopaminergic neurites and dopamine levels. Although both secreted and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lindström, Riitta, Lindholm, Päivi, Kallijärvi, Jukka, Yu, Li-ying, Piepponen, T. Petteri, Arumäe, Urmas, Saarma, Mart, Heino, Tapio I.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760817/
https://ncbi.nlm.nih.gov/pubmed/24019940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073928
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