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Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy
Cerebral dopamine neurotrophic factor (CDNF) shows beneficial effects in rodent models of Parkinson’s and Alzheimer’s disease. The brain is a challenging target for protein therapy due to its exclusive blood–brain barrier. Hence, the therapeutic protein should be delivered directly to the brain pare...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publishing
2019-04-01
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Colecção: | Cell Transplantation |
Acesso em linha: | https://doi.org/10.1177/0963689719827943 |
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