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Folate-conjugated immunoglobulin targets melanoma tumor cells for NK cell effector functions

The folate receptor (FR) is over-expressed on the vascular side of cancerous cells including those of the breast, ovaries, testes, and cervix. We hypothesized that a folate-conjugated immunoglobulin (F-IgG) would bind to the FR that is over-expressed on melanoma tumor cells to target these cells for...

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Publicado en:Melanoma Res
Main Authors: Skinner, Cassandra C., McMichael, Elizabeth L., Jaime-Ramirez, Alena C., Abrams, Zachary B., Lee, Robert J., Carson, William E.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927392/
https://ncbi.nlm.nih.gov/pubmed/27035691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000258
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