NK Cell–Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin are Enhanced by Cytokines

Optimally effective antitumor therapies would not only activate immune effector cells, but engage them at the tumor. Folate-conjugated to immunoglobulin (F-IgG) could direct innate immune cells with Fc receptors to folate receptor–expressing cancer cells. F-IgG bound to human KB and HeLa cells, as w...

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Bibliografski detalji
Izdano u:Cancer Immunol Res
Glavni autori: Jaime-Ramirez, Alena C., McMichael, Elizabeth, Kondadasula, SriVidya, Skinner, Cassandra C., Mundy-Bosse, Bethany L., Luedke, Eric, Jones, Natalie B., Mani, Aruna, Roda, Julie, Karpa, Volodymyr, Li, Hong, Li, Jilong, Elavazhagan, Saranya, La Perle, Krista M., Schmitt, Alessandra C., Lu, Yanhui, Zhang, Xiaoli, Pan, Xueliang, Mao, Hsaioyin, Davis, Melanie, Jarjoura, David, Butchar, Jonathan P., Poi, Ming, Phelps, Mitch, Tridandapani, Susheela, Byrd, John C., Caligiuri, Michael A., Lee, Robert J., Carson, William E.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818694/
https://ncbi.nlm.nih.gov/pubmed/26865456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0168
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