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xTract: software for characterizing conformational changes of protein complexes by quantitative cross-linking mass spectrometry

Chemical cross-linking in combination with mass spectrometry generates distance restraints of amino acid pairs in close proximity on the surface of native proteins and protein complexes. In this study we used quantitative mass spectrometry and chemical cross-linking to quantify differences in cross-...

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Publicat a:Nat Methods
Autors principals: Walzthoeni, Thomas, Joachimiak, Lukasz A, Rosenberger, George, Röst, Hannes L, Malmström, Lars, Leitner, Alexander, Frydman, Judith, Aebersold, Ruedi
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927332/
https://ncbi.nlm.nih.gov/pubmed/26501516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3631
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