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Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

The study of proteins and protein complexes using chemical cross-linking followed by the MS identification of the cross-linked peptides has found increasingly widespread use in recent years. Thus far, such analyses have used almost exclusively homobifunctional, amine-reactive cross-linking reagents....

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Main Authors: Leitner, Alexander, Joachimiak, Lukasz A., Unverdorben, Pia, Walzthoeni, Thomas, Frydman, Judith, Förster, Friedrich, Aebersold, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4084482/
https://ncbi.nlm.nih.gov/pubmed/24938783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320298111
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