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Pilin Vaccination Stimulates Weak Antibody Responses and Provides No Protection in a C57Bl/6 Murine Model of Acute Clostridium difficile Infection

Clostridium difficile is the leading cause of nosocomial infections in the United States, adding billions of dollars per year to health care costs. A vaccine targeted against the bacterium would be extremely beneficial in decreasing the morbidity and mortality caused by C. difficile-associated disea...

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Detalhes bibliográficos
Publicado no:J Vaccines Vaccin
Main Authors: Maldarelli, Grace A, Matz, Hanover, Gao, Si, Chen, Kevin, Hamza, Therwa, Yfantis, Harris G, Feng, Hanping, Donnenberg, Michael S
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4927082/
https://ncbi.nlm.nih.gov/pubmed/27375958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7560.1000321
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