Knockdown of AMPKα2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway

It has been shown that activation of adenosine monophosphate-activated protein kinase (AMPK) suppresses proliferation of a variety of tumor cells as well as nonmalignant cells. In this study, we used post-transcriptional gene silencing with small interfering RNA (siRNA) to specifically examine the e...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ke, Rui, Liu, Lu, Zhu, Yanting, Li, Shaojun, Xie, Xinming, Li, Fangwei, Song, Yang, Yang, Lan, Gao, Li, Li, Manxiang
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926378/
https://ncbi.nlm.nih.gov/pubmed/27258250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17060844
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