Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway

Activation of the Notch3 cascade is involved in the development of pulmonary arterial hypertension by stimulating the proliferation of vascular smooth muscle cells. However, the detailed molecular mechanisms underlying this effect are still unclear. The present study aims to address this issue. We d...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Song, Yang, Zhang, Yonghong, Jiang, Haoxiang, Zhu, Yanting, Liu, Lu, Feng, Wei, Yang, Lan, Wang, Yibin, Li, Manxiang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556730/
https://ncbi.nlm.nih.gov/pubmed/26380809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.08.007
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