Activation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathway

Activation of the Notch3 cascade is involved in the development of pulmonary arterial hypertension by stimulating the proliferation of vascular smooth muscle cells. However, the detailed molecular mechanisms underlying this effect are still unclear. The present study aims to address this issue. We d...

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Detaylı Bibliyografya
Yayımlandı:FEBS Open Bio
Asıl Yazarlar: Song, Yang, Zhang, Yonghong, Jiang, Haoxiang, Zhu, Yanting, Liu, Lu, Feng, Wei, Yang, Lan, Wang, Yibin, Li, Manxiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2015
Konular:
Research article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556730/
https://ncbi.nlm.nih.gov/pubmed/26380809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.08.007
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