Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice

Hypercholesterolemia is a well-established risk factor for kidney injury, which can lead to chronic kidney disease (CKD). Osteopontin (OPN) has been implicated in the pathology of several renal conditions. This study was to evaluate the effects of OPN on hypercholesterolemia induced renal dysfunctio...

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Pubblicato in:Sci Rep
Autori principali: Pei, Zouwei, Okura, Takafumi, Nagao, Tomoaki, Enomoto, Daijiro, Kukida, Masayoshi, Tanino, Akiko, Miyoshi, Ken-ichi, Kurata, Mie, Higaki, Jitsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926090/
https://ncbi.nlm.nih.gov/pubmed/27353458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28882
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