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Osteopontin deficiency reduces kidney damage from hypercholesterolemia in Apolipoprotein E-deficient mice

Hypercholesterolemia is a well-established risk factor for kidney injury, which can lead to chronic kidney disease (CKD). Osteopontin (OPN) has been implicated in the pathology of several renal conditions. This study was to evaluate the effects of OPN on hypercholesterolemia induced renal dysfunctio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pei, Zouwei, Okura, Takafumi, Nagao, Tomoaki, Enomoto, Daijiro, Kukida, Masayoshi, Tanino, Akiko, Miyoshi, Ken-ichi, Kurata, Mie, Higaki, Jitsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926090/
https://ncbi.nlm.nih.gov/pubmed/27353458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28882
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