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AXL receptor tyrosine kinase is required for T cell priming and antiviral immunity

The receptor tyrosine kinase (RTK) AXL is induced in response to type I interferons (IFNs) and limits their production through a negative feedback loop. Enhanced production of type I IFNs in Axl(-/-)dendritic cells (DCs) in vitro have led to speculation that inhibition of AXL would promote antiviral...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Schmid, Edward T, Pang, Iris K, Carrera Silva, Eugenio A, Bosurgi, Lidia, Miner, Jonathan J, Diamond, Michael S, Iwasaki, Akiko, Rothlin, Carla V
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924996/
https://ncbi.nlm.nih.gov/pubmed/27350258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12414
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