The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer

The receptor tyrosine kinases (RTKs) TYRO3, AXL and MERTK (TAM) have well-described oncogenic functions in a number of cancers. Notwithstanding, TAM RTKs are also potent and indispensable inhibitors of inflammation. The combined deletion of Axl and Mertk in mice enhances chronic inflammation and aut...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Uribe, Diana J., Mandell, Edward K., Watson, Adam, Martinez, Jesse D., Leighton, Jonathan A., Ghosh, Sourav, Rothlin, Carla V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519024/
https://ncbi.nlm.nih.gov/pubmed/28727830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179979
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