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Macrophage AXL receptor tyrosine kinase inflames the heart after reperfused myocardial infarction

Tyro3, AXL, and MerTK (TAM) receptors are activated in macrophages in response to tissue injury and as such have been proposed as therapeutic targets to promote inflammation resolution during sterile wound healing, including myocardial infarction. Although the role of MerTK in cardioprotection is we...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: DeBerge, Matthew, Glinton, Kristofor, Subramanian, Manikandan, Wilsbacher, Lisa D., Rothlin, Carla V., Tabas, Ira, Thorp, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954597/
https://ncbi.nlm.nih.gov/pubmed/33529176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139576
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