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TAM Receptor Signaling in Immune Homeostasis
The TAM receptor tyrosine kinases (RTKs)—TYRO3, AXL, and MERTK—together with their cognate agonists GAS6 and PROS1 play an essential role in the resolution of inflammation. Deficiencies in TAM signaling have been associated with chronic inflammatory and autoimmune diseases. Three processes regulated...
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| Published in: | Annu Rev Immunol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4491918/ https://ncbi.nlm.nih.gov/pubmed/25594431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032414-112103 |
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