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Syndromic deafness mutations at Asn 14 differentially alter the open stability of Cx26 hemichannels
Connexin 26 (Cx26) is a transmembrane protein that forms hexameric hemichannels that can function when unopposed or dock to form intercellular gap junction channels. Aberrantly functioning unopposed hemichannels are a common feature of syndromic deafness associated with mutations in Cx26. In this st...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4924935/ https://ncbi.nlm.nih.gov/pubmed/27353444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201611585 |
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