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Enzyme Substrate Complex of the H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Mössbauer and Computational Studies

The extradiol, aromatic ring-cleaving enzyme homoprotocatechuate 2,3-dioxygenase (HPCD) catalyzes a complex chain of reactions that involve second sphere residues of the active site. The importance of the 2(nd)-sphere residue His200 was demonstrated in studies of HPCD variants, such as His200Cys (H2...

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Detalhes bibliográficos
Publicado no:Inorg Chem
Main Authors: Meier, Katlyn K., Rogers, Melanie S., Kovaleva, Elena G., Lipscomb, John D., Bominaar, Emile L., Münck, Eckard
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924929/
https://ncbi.nlm.nih.gov/pubmed/27275865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.6b00148
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