A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization

The heteromeric membrane protein Organic Solute Transporter alpha/beta is the major bile acid efflux transporter in the intestine. Physical association of its alpha and beta subunits is essential for their polarized basolateral membrane localization and function in the transport of bile acids and ot...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xu, Shuhua, Soroka, Carol J., Sun, An-Qiang, Backos, Donald S., Mennone, Albert, Suchy, Frederick J., Boyer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924846/
https://ncbi.nlm.nih.gov/pubmed/27351185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158269
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