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Synthesis of a Peptide-Universal Nucleotide Antigen: Towards Next-Generation Antibodies to Detect Topoisomerase I-DNA Covalent Complexes
The topoisomerase (topo) I-DNA covalent complex represents an attractive target for developing diagnostic antibodies to measure responsiveness to drugs. We report a new antigen, peptide 2, and four murine monoclonal antibodies raised against 2 that exhibit excellent specificity for recognition of 2...
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| Vydáno v: | Org Biomol Chem |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922793/ https://ncbi.nlm.nih.gov/pubmed/27113574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02049b |
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