MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension

Loss of the growth-suppressive effects of bone morphogenetic protein (BMP) signaling has been demonstrated to promote pulmonary arterial endothelial cell dysfunction and induce pulmonary arterial smooth muscle cell (PASMC) proliferation, leading to the development of pulmonary arterial hypertension...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rothman, Alexander M.K., Arnold, Nadine D., Pickworth, Josephine A., Iremonger, James, Ciuclan, Loredana, Allen, Robert M.H., Guth-Gundel, Sabine, Southwood, Mark, Morrell, Nicholas W., Thomas, Matthew, Francis, Sheila E., Rowlands, David J., Lawrie, Allan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922709/
https://ncbi.nlm.nih.gov/pubmed/27214554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83361
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